http://www.cbr.com/gambit-15-ways-to-make-a-good-movie/ fluff
That was a fun read! The Sinister angle seems like it would be the most rewarding for Fox, story wise. It would give them a chance to present a schemer and experimenter whose depravity surpasses, from the movies, Stryker's.
It would be pretty awesome if they went for a cleverness and not just persistence in a hero. They could do something like having the Thirty Six Stratagems as the basis of Remy's action, revealing it at the end sort of like Ocean's 11; a quick series of scenes showing the prior reckless actions, that Gambit is prone to, all had a purpose. If they have the book in the original Chinese, they have a quick way of showing two different characters took the time to learn another language; Gambit and whomever reads it. Which would be a cool way to introduce another of the X-Men.
I do like their idea of Sinister and Gambit as mentor and unwilling protege. It would be kind of cool if they built a Gambit franchise around Sinister being his long term antagonist as it would give it something a lot of the other X-men films don't have. I suppose you could say Charles vs Magneto but Magneto flirts with being good too much whereas this would be more of a pure good vs evil with the evil continually pushing Gambit into bad decisions.
This would also be a chance to portray it as the deeply flawed, all too human character vs evil